Top Artificial Intelligence Startups in USA

Browse 40 startups in USA working in Artificial Intelligence. Every listing below is matched on location and skill set so you can discover the right company faster. Compare profiles and reach out directly.

FlyCode

Boston

FlyCode, a Y Combinator Summer 2022 company, is building the retention layer designed specifically to stop subscription businesses from losing revenue to failed payments. Every subscription business, from the largest SaaS platforms to the latest consumer streaming services, loses a surprising amount of revenue to a deeply unglamorous problem: the payment that simply does not […]

Artificial Intelligence E-commerce Fintech

Flair Labs

San Francisco

Flair Labs, a Y Combinator-backed startup, is betting that the next wave of productivity in real estate and mortgage lending will come not from better CRMs but from autonomous agents that handle the communication workflow itself. Real estate and mortgage lending are two of the most communication-intensive industries in the economy. Every transaction generates hundreds […]

AI AI Assistant Artificial Intelligence

Speedy Labs

San Francisco

Speedy Labs, a Y Combinator Winter 2023 company, is taking aim at a financial problem that quietly drains billions of dollars from manufacturers and distributors every year: the opaque, spreadsheet-driven world of rebate management. Founded in 2023 by Jatin Mehta, Ranti Dev Sharma, and Ayush Jasuja, Speedy Labs offers an AI-powered platform that helps industrial […]

Artificial Intelligence B2B Generative AI

kapa.ai

New York

When OpenAI, N8N, Mapbox, Mixpanel, Nokia, and Grafana all lean on the same startup to answer their users’ technical questions, something interesting is happening beneath the surface of the AI hype cycle. That startup is kapa.ai, a Summer 2023 Y Combinator company founded in 2023 by Emil Soerensen and Finn Bauer, and it has methodically […]

AI AI Assistant Artificial Intelligence

Morph

San Francisco

San Francisco, CA — The first generation of AI coding assistants proved that language models could write code. The next generation is about something harder: agents that can work inside real codebases for long-running, multi-step engineering tasks without getting slow, expensive, or unreliable. Morph, a Y Combinator Summer 2023 company based in San Francisco, is […]

AI API Artificial Intelligence

sync.

San Francisco

sync., an AI lipsync tool for video content creators and a Y Combinator Winter 2024 company, is drawing industry attention as it scales operations following its accelerator cohort. The company’s mission is to make video as fluid and editable as a word document — letting creators record once, revise at will, and post, without re-recording […]

AI Artificial Intelligence B2B

Alai

San Francisco

Alai, a Winter 2024 Y Combinator company, is making the case that the presentation itself is overdue for reinvention. As knowledge workers increasingly measure their weeks in slide decks, the company — founded in 2023 by Anmol Sood and Krishna Gupta — has built an AI presentation tool designed around a simple promise: bring your […]

AI Artificial Intelligence Productivity

VideoGen

San Francisco

VideoGen, a Summer 2024 Y Combinator-backed startup, is taking on one of the most universally painful problems in content creation: making professional video is hard, slow, and expensive. Founded in 2023 by Anton Koenig and David Grossman, VideoGen lets anyone generate professional, copyright-free videos in seconds using AI — a proposition that has already won […]

AI Artificial Intelligence Developer Tools

Roark

San Francisco

Roark, a Y Combinator Winter 2025 company, is betting that the difference between a novelty and a trustworthy product comes down to rigorous, automated testing — and it is building the platform to make that possible. As enterprises race to deploy voice agents for customer support, sales, and operations, a quieter problem has surfaced behind […]

AI Analytics Artificial Intelligence

Piggy Robotics

Mountain View

Piggy Robotics, a Y Combinator Fall 2025 company, is betting that the next great scaling law in robotics will not come from bigger motors or heavier actuators, but from rethinking the body itself. The startup is building humanoid robots designed to fold your laundry, load your dishwasher, and tidy up the kitchen — at a […]

Artificial Intelligence Home Automation Robotics

Wildcard

San Francisco

A new layer of commerce is forming inside AI assistants, and most brands cannot yet see what is happening inside it. When a shopper asks ChatGPT, Gemini, Claude, or another AI assistant to recommend running shoes, protein powder, office supplies, or a lightweight laptop, an entirely new buying journey unfolds. It is not a search […]

Artificial Intelligence E-commerce Generative AI

Proception Inc.

Mountain View

Proception Inc, a Y Combinator Winter 2025 company, is focused squarely on making humanoid robots dexterous enough to handle the delicate, high-precision manipulation tasks that define most useful human work. Humanoid robots have made remarkable progress in locomotion over the past few years, but the real test of utility has always been what a robot […]

AI Artificial Intelligence B2B

Telemetron

San Francisco

Telemetron, a Y Combinator Fall 2025 company, is building an AI-powered support and operations platform tailored for hardware products — and going after a category that most modern support platforms quietly ignore: the messy, high-stakes world of hardware customer support. The platform serves medical devices, consumer electronics, industrial hardware, robotics, and the rest of the […]

Artificial Intelligence B2B Developer Tools

Zolvo

San Francisco

Zolvo, a startup in Y Combinator’s Spring 2026 batch, is building AI to replace the outdated software stack that commercial lenders in the United States have relied on for decades. These lenders collectively manage nearly $2.9 trillion in outstanding commercial and industrial loans — yet the tools used to service those portfolios still look like they […]

Artificial Intelligence B2B Lending

Cortex AI

San Francisco

Cortex AI, a Y Combinator Fall 2025 company, is racing to build that missing dataset and become the data backbone for the labs training the next generation of robots. The AI revolution of the past five years was built on the back of internet-scale data. Trillions of words and billions of images turned out to […]

Artificial Intelligence Reinforcement Learning Robotics

Cactus

San Francisco

Cactus is a Y Combinator Summer 2025 company built on a simple but hard conviction: the next frontier of consumer AI isn’t in the cloud — it’s on the device in your pocket or on your wrist. Founded in 2025 and based in San Francisco, the eight-person team is building a low-latency AI engine optimized […]

AI Artificial Intelligence Developer Tools

Wavedash

San Francisco

Wavedash, founded in 2024 and based in San Francisco, is wagering on a simple but powerful proposition: the web is still the most frictionless distribution surface ever built, and modern browser capabilities — WebAssembly, WebGPU, modern audio APIs, and rapidly improving streaming infrastructure — finally make it possible to deliver “world class games on the […]

Artificial Intelligence Consumer Gaming

Signals

San Francisco

Most customer support software is built around a reactive loop: a user runs into a problem, opens a ticket, waits in a queue, and eventually gets an answer. Signals, a Y Combinator Winter 2026 startup, is flipping that model on its head. The company is building an AI customer engagement platform that engages high-value customers […]

Artificial Intelligence B2B SaaS

Caddy

New York

Most “AI assistants” today still wait for you to ask. Caddy, a Y Combinator Fall 2025 startup founded by alumni of Loom’s AI team, is taking a different approach: an AI personal assistant app that lives in your Messages, reaches out when something needs your attention, and gets work done across the tools you already […]

Artificial Intelligence Productivity SaaS

Slashy

San Francisco

Email remains the universal input tray of knowledge work, and despite two decades of startup promises, most professionals still spend hours a day on it. Slashy, a Y Combinator Summer 2025 company, is taking another run at the category with an AI email assistant it describes as ‘Cursor for Email’ – an agent designed to […]

Artificial Intelligence Email

Frizzle

San Francisco

Frizzle, a Y Combinator Summer 2025 company based in San Francisco, has built an AI product aimed squarely at one of the most stubborn time sinks in American education: grading. Teachers routinely spend more than 10 hours per week – roughly a quarter of all their working time – evaluating student work, especially handwritten math […]

Artificial Intelligence B2B Education

Embedder

San Francisco

The AI-driven coding wave has reshaped how cloud, web, and application engineers work – autocomplete, copilots, and agents are now table stakes for high-level software development. But there is one category of code that has been stubbornly left out: firmware. The low-level C, assembly, and RTOS-adjacent code that runs on microcontrollers, radios, motor drivers, medical […]

Artificial Intelligence B2B Developer Tools

Eden

New York

Sales reps learn to sell by doing. The problem is that most of the doing happens on live prospects, where a blown discovery question or a fumbled objection costs real pipeline. Eden, a Y Combinator Summer 2025 startup, is building the practice layer that comes before the live call — an AI buyer simulator that […]

Artificial Intelligence B2B Sales Enablement

Autosana

San Francisco

Coding agents have gotten remarkably good at writing code. They’re still not great at proving that their code actually works. Autosana, a Summer 2025 Y Combinator company, is out to close that gap with an end-to-end testing layer purpose-built for AI coding agents, covering iOS, Android, and Web apps at once. Autosana’s promise to developers […]

Artificial Intelligence B2B Developer Tools

Hypercubic

San Francisco

Hypercubic, a Fall 2025 Y Combinator-backed startup, is tackling one of the most valuable and least glamorous technology problems in the global economy: the decades-old COBOL codebases running on mainframes that continue to power the core systems of banks, insurers, airlines, telecoms, and retailers. The company is building an AI-native platform to maintain, understand, and […]

Artificial Intelligence B2B Developer Tools

Unsiloed AI

San Francisco

Enterprise AI projects tend to fail at a specific, unglamorous step: parsing the documents. Research teams can spend six months building a document pipeline and still watch fewer than ten percent of those projects make it into production, because generic large language model parsers and legacy OCR systems fall apart on the multimodal PDFs, scanned […]

APIs Artificial Intelligence B2B

Didit

San Francisco

As fraud costs balloon across the internet and KYC-heavy industries juggle an ever-growing stack of identity checks, Didit is pitching a simpler story: one platform, one fast face scan, one predictable per-use price. Founded in 2023 and currently part of Y Combinator’s Winter 2026 cohort, Didit positions itself as “an all-in-one identity platform that lets […]

Artificial Intelligence B2B Fintech

Sourcebot

San Francisco

Sourcebot, an AI code search tool built for massive codebases, is emerging from Y Combinator’s Fall 2025 batch with a message the rest of the AI tooling industry has been slow to embrace. Writing code is no longer the hard part – understanding it is. And for both human engineers and the AI agents increasingly […]

Artificial Intelligence B2B Developer Tools

Zalos

San Francisco

Zalos, a Fall 2025 Y Combinator company, is taking direct aim at the repetitive, time-consuming, and error-prone work that still clogs finance operations at companies of every size. The startup builds AI finance automation software – computer-using agents that log directly into a company’s existing ERP, accounting systems, banking portals, and other CFO tools – […]

Artificial Intelligence B2B Fintech

Corvera

San Francisco

Consumer packaged goods brands have long been celebrated for their marketing and product innovation, but their back-office operations remain stuck in the spreadsheet era. Corvera, a Y Combinator–backed startup, is attacking that gap with an AI agent workforce purpose-built for CPG operations – and the early traction suggests the market has been waiting for exactly […]

Artificial Intelligence B2B SaaS
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