Browse 30 startups in USA working in AI. Every listing below is matched on location and skill set so you can discover the right company faster. Compare profiles and reach out directly.
Peoplebox.ai is trying to do something most HR tech companies only gesture at: rebuild the entire talent stack from the ground up around AI. Founded in 2018 by Abhinav Chugh and Alagu M, the San Francisco-based company joined Y Combinator’s Summer 2022 batch and has since grown into an AI-native platform used by more than […]
Flair Labs, a Y Combinator-backed startup, is betting that the next wave of productivity in real estate and mortgage lending will come not from better CRMs but from autonomous agents that handle the communication workflow itself. Real estate and mortgage lending are two of the most communication-intensive industries in the economy. Every transaction generates hundreds […]
Careforce, a Y Combinator Fall 2024 company, is tackling a coordination crisis in healthcare with a distinctive pitch: AI workers purpose-built to help healthcare organizations find, call, and schedule more patients. Healthcare organizations across the United States are buckling under a crisis that has little to do with medicine itself. Patients fall through the cracks […]
Superglue, a Winter 2025 Y Combinator company, is attacking one of the least glamorous and most fragile layers of the modern enterprise stack: the brittle SQL scripts, cron jobs, and one-off connectors that quietly run most day-to-day operations. Founded in 2024 by Adina Goerres and Stefan Faistenauer, the four-person team is building an open-source platform […]
When OpenAI, N8N, Mapbox, Mixpanel, Nokia, and Grafana all lean on the same startup to answer their users’ technical questions, something interesting is happening beneath the surface of the AI hype cycle. That startup is kapa.ai, a Summer 2023 Y Combinator company founded in 2023 by Emil Soerensen and Finn Bauer, and it has methodically […]
San Francisco, CA — The first generation of AI coding assistants proved that language models could write code. The next generation is about something harder: agents that can work inside real codebases for long-running, multi-step engineering tasks without getting slow, expensive, or unreliable. Morph, a Y Combinator Summer 2023 company based in San Francisco, is […]
Alex, a Y Combinator Winter 2024 company, is betting that an AI recruiter can do that first conversation not just faster, but better, and the company’s early momentum suggests a lot of employers agree. The first real filter in most hiring processes is still a phone screen: a harried recruiter, a candidate balancing their calendar, […]
Onyx, a Y Combinator Winter 2024 company, is building the open-source AI chat layer designed to solve one of the most persistent problems in modern work: inside every company is a mountain of knowledge that nobody can find. It is scattered across Google Drive, Slack threads, GitHub repos, Confluence pages, Salesforce notes, Notion wikis, and […]
sync., an AI lipsync tool for video content creators and a Y Combinator Winter 2024 company, is drawing industry attention as it scales operations following its accelerator cohort. The company’s mission is to make video as fluid and editable as a word document — letting creators record once, revise at will, and post, without re-recording […]
Alai, a Winter 2024 Y Combinator company, is making the case that the presentation itself is overdue for reinvention. As knowledge workers increasingly measure their weeks in slide decks, the company — founded in 2023 by Anmol Sood and Krishna Gupta — has built an AI presentation tool designed around a simple promise: bring your […]
VideoGen, a Summer 2024 Y Combinator-backed startup, is taking on one of the most universally painful problems in content creation: making professional video is hard, slow, and expensive. Founded in 2023 by Anton Koenig and David Grossman, VideoGen lets anyone generate professional, copyright-free videos in seconds using AI — a proposition that has already won […]
Roark, a Y Combinator Winter 2025 company, is betting that the difference between a novelty and a trustworthy product comes down to rigorous, automated testing — and it is building the platform to make that possible. As enterprises race to deploy voice agents for customer support, sales, and operations, a quieter problem has surfaced behind […]
Cedar, a Winter 2025 Y Combinator company, is building a new kind of copilot that picks up where the training program ends — one that captures the playbook of the best reps and puts it in front of every AE, every day. The hardest part of scaling a go-to-market team isn’t hiring — it’s ramping. […]
ISSEN, a Y Combinator Fall 2024 company, is betting that real-time voice AI can finally close the gap between vocabulary drills and real conversation — and has built an AI conversational tutor designed to make fluency, not streaks, the goal. Language apps have gotten very good at vocabulary drills and very bad at conversation. Most […]
Proception Inc, a Y Combinator Winter 2025 company, is focused squarely on making humanoid robots dexterous enough to handle the delicate, high-precision manipulation tasks that define most useful human work. Humanoid robots have made remarkable progress in locomotion over the past few years, but the real test of utility has always been what a robot […]
Frekil, a Y Combinator-backed startup, is on a mission to collapse the timeline for generating real-world evidence in the pharmaceutical and biotech industries — from months to minutes. In sectors where regulators rely on real-world evidence (RWE) to confirm drug safety, payers use it to negotiate pricing, and manufacturers need it to expand indications and […]
Lilac, a Y Combinator Summer 2025 company, is on a mission to turn idle GPU capacity into a market — automatically. The same data centers that everyone is racing to fill with new GPUs are sitting on a quieter problem: a meaningful share of the silicon they already have is idle at any given moment. […]
Cactus is a Y Combinator Summer 2025 company built on a simple but hard conviction: the next frontier of consumer AI isn’t in the cloud — it’s on the device in your pocket or on your wrist. Founded in 2025 and based in San Francisco, the eight-person team is building a low-latency AI engine optimized […]
Shor, a fintech startup in Y Combinator’s Summer 2025 batch, is betting that the next generation of global payroll will run on stablecoins and AI agents rather than on legacy banking rails. The company has launched what it calls an AI-native Employer-of-Record, aimed at giving remote teams a faster, cheaper, and fully compliant way to […]
Children’s entertainment is in an awkward moment. YouTube and Netflix produce more content than any kid could watch in a lifetime, but parents increasingly find it overstimulating, repetitive, and short on the kind of imaginative play that earlier generations took for granted. Pixley AI, a Y Combinator Fall 2025 startup, is betting that the answer […]
The first wave of AI-powered app builders fixed an obvious problem: shipping a usable frontend from a prompt. Tools like Lovable and v0 compressed hours of component tweaking into a few iterative descriptions, letting non-engineers and engineers alike move faster than ever on the user-facing layer. VibeFlow, a Y Combinator Summer 2025 company, is building […]
Loan servicing and collections has historically been one of the most labor-intensive – and most regulated – corners of consumer finance. Lenders need to recover delinquent balances, treat borrowers respectfully, and stay within an ever-tightening compliance perimeter, all while keeping the cost-to-collect manageable. Veritus, a Y Combinator Summer 2025 company based in San Francisco, is […]
Inside a private equity firm, the most numerate, sleep-deprived people in the building are usually the associates. They build leveraged buyout models, dissect confidential information memoranda, draft investment committee memos, update CRMs, and chase down the long tail of diligence questions that turn an idea into a deal. Zarna, a Y Combinator Fall 2025 startup […]
Drug development has long been hobbled by a quietly devastating problem: the same medicine that works for one patient can prove ineffective – or even toxic – for the next. Increasingly, the suspect is the trillions of microbes living inside us. Anto Biosciences, a Y Combinator Fall 2025 company, believes microbiome drug development can finally […]
For a generation of mechanical engineers, the everyday experience of CAD has been defined by a handful of incumbents – Solidworks, NX, Creo, Catia, Fusion 360, Onshape – and a strangely consistent set of complaints. The software is slow. Files take minutes (sometimes hours) to open. Design workflows are tedious, multi-step, and hostile to iteration. […]
Management consultants have long charged seven-figure fees to do one seemingly simple thing: talk to everyone in a company and figure out what’s broken. Ontora, a San Francisco-based startup in Y Combinator’s Spring 2026 batch, is betting that the whole exercise can be automated. The company has launched an AI operational intelligence platform that interviews […]
Food tracking apps have a retention problem. Calorie counters promise transformation but demand tedium, and most users churn within a few weeks. Paper Star, a San Francisco startup in Y Combinator’s Spring 2026 batch, thinks the category needs a rebuild – one that trades spreadsheets for stories. Its first product, Napkin Math, is an AI-powered […]
Ask any plant manager where the bottlenecks are and the answer rarely involves the factory floor itself. It is the paperwork around it – the RFQs that need processing, the quotes that need chasing, the suppliers that need reminding, and the production schedules that need rewiring every time reality intrudes. Korso, a Y Combinator Spring […]
Outbound sales has become an arms race of volume, and small teams are losing. Cold lists, mass sequences, and blanket personalization tools have driven reply rates to historic lows while inboxes become harder to crack. Gojiberry AI, a Y Combinator Spring 2026 company, is pitching a different approach: an AI outbound sales platform with a […]
Developer documentation has always been the quiet infrastructure of software. It determines which APIs get adopted, which SDKs get abandoned, and which products get replaced. Manicule, a Y Combinator Spring 2026 startup, believes that infrastructure is overdue for a rebuild – and that the rebuild looks more like an AI-native studio than a freelance writing […]
