Browse 40 startups in San Francisco working in B2B. Every listing below is matched on location and skill set so you can discover the right company faster. Compare profiles and reach out directly.
Peoplebox.ai is trying to do something most HR tech companies only gesture at: rebuild the entire talent stack from the ground up around AI. Founded in 2018 by Abhinav Chugh and Alagu M, the San Francisco-based company joined Y Combinator’s Summer 2022 batch and has since grown into an AI-native platform used by more than […]
Pierre, a Y Combinator Winter 2023 company, is building a new, opinionated git platform designed for the way modern software teams actually work. Founded in 2023 by Jacob Thornton and Ian Ownbey, the company is rethinking code hosting, code review, and continuous integration from the ground up, with small, focused teams and AI-augmented workflows at […]
PrimeVault, a Y Combinator Summer 2022 company, is building what it calls the all-in-one digital asset and stablecoin platform for enterprises and financial institutions. As stablecoins move from crypto curiosity to serious financial infrastructure, the companies issuing, holding, and moving them are running into a familiar problem: enterprise-grade tooling has not caught up with enterprise-grade […]
Metal, a Y Combinator Winter 2023 company, is betting that the entire fundraising workflow is due for an AI-native rebuild. Fundraising has always been one of the most information-asymmetric processes in business. Founders scramble to identify which of thousands of investors might actually fit their stage, sector, and geography. Growth-stage executives piece together LP relationship […]
Speedy Labs, a Y Combinator Winter 2023 company, is taking aim at a financial problem that quietly drains billions of dollars from manufacturers and distributors every year: the opaque, spreadsheet-driven world of rebate management. Founded in 2023 by Jatin Mehta, Ranti Dev Sharma, and Ayush Jasuja, Speedy Labs offers an AI-powered platform that helps industrial […]
Alex, a Y Combinator Winter 2024 company, is betting that an AI recruiter can do that first conversation not just faster, but better, and the company’s early momentum suggests a lot of employers agree. The first real filter in most hiring processes is still a phone screen: a harried recruiter, a candidate balancing their calendar, […]
sync., an AI lipsync tool for video content creators and a Y Combinator Winter 2024 company, is drawing industry attention as it scales operations following its accelerator cohort. The company’s mission is to make video as fluid and editable as a word document — letting creators record once, revise at will, and post, without re-recording […]
Aravolta, a Y Combinator-backed company, is building the unified software layer that data center operators have long wanted. Data centers have become the beating heart of the AI economy, but the software running them is often surprisingly primitive. Operators juggle a patchwork of tools to track power usage, environmental conditions, and hardware health — tools […]
Cedar, a Winter 2025 Y Combinator company, is building a new kind of copilot that picks up where the training program ends — one that captures the playbook of the best reps and puts it in front of every AE, every day. The hardest part of scaling a go-to-market team isn’t hiring — it’s ramping. […]
OrgOrg, a Y Combinator-backed startup founded by serial entrepreneur Wayne Crosby, is rolling out a new generation of organizational productivity tools designed to keep teams healthy and aligned as they scale. Positioned as a natural extension of Google Workspace, OrgOrg’s suite of applications helps companies of every size collaborate more effectively and move faster. Crosby […]
Frekil, a Y Combinator-backed startup, is on a mission to collapse the timeline for generating real-world evidence in the pharmaceutical and biotech industries — from months to minutes. In sectors where regulators rely on real-world evidence (RWE) to confirm drug safety, payers use it to negotiate pricing, and manufacturers need it to expand indications and […]
Probo, part of Y Combinator’s Spring 2025 batch, is launching with a simple promise to early-stage companies: stop losing weeks to compliance. The company positions itself as a fully outsourced compliance team, handling everything from setting requirements to running the audit, so founders can focus on building their business instead of managing SOC 2 and […]
Telemetron, a Y Combinator Fall 2025 company, is building an AI-powered support and operations platform tailored for hardware products — and going after a category that most modern support platforms quietly ignore: the messy, high-stakes world of hardware customer support. The platform serves medical devices, consumer electronics, industrial hardware, robotics, and the rest of the […]
Zolvo, a startup in Y Combinator’s Spring 2026 batch, is building AI to replace the outdated software stack that commercial lenders in the United States have relied on for decades. These lenders collectively manage nearly $2.9 trillion in outstanding commercial and industrial loans — yet the tools used to service those portfolios still look like they […]
Bond, a San Francisco startup in Y Combinator’s Spring 2025 batch, is taking aim at one of the most universal complaints in modern corporate life: executives drowning in status updates, dashboards, messages, and meetings they don’t have time to parse. The company is building an AI Chief of Staff that sits quietly across a company’s […]
Shor, a fintech startup in Y Combinator’s Summer 2025 batch, is betting that the next generation of global payroll will run on stablecoins and AI agents rather than on legacy banking rails. The company has launched what it calls an AI-native Employer-of-Record, aimed at giving remote teams a faster, cheaper, and fully compliant way to […]
Most customer support software is built around a reactive loop: a user runs into a problem, opens a ticket, waits in a queue, and eventually gets an answer. Signals, a Y Combinator Winter 2026 startup, is flipping that model on its head. The company is building an AI customer engagement platform that engages high-value customers […]
Frizzle, a Y Combinator Summer 2025 company based in San Francisco, has built an AI product aimed squarely at one of the most stubborn time sinks in American education: grading. Teachers routinely spend more than 10 hours per week – roughly a quarter of all their working time – evaluating student work, especially handwritten math […]
The AI-driven coding wave has reshaped how cloud, web, and application engineers work – autocomplete, copilots, and agents are now table stakes for high-level software development. But there is one category of code that has been stubbornly left out: firmware. The low-level C, assembly, and RTOS-adjacent code that runs on microcontrollers, radios, motor drivers, medical […]
Coding agents have gotten remarkably good at writing code. They’re still not great at proving that their code actually works. Autosana, a Summer 2025 Y Combinator company, is out to close that gap with an end-to-end testing layer purpose-built for AI coding agents, covering iOS, Android, and Web apps at once. Autosana’s promise to developers […]
The first wave of AI-powered app builders fixed an obvious problem: shipping a usable frontend from a prompt. Tools like Lovable and v0 compressed hours of component tweaking into a few iterative descriptions, letting non-engineers and engineers alike move faster than ever on the user-facing layer. VibeFlow, a Y Combinator Summer 2025 company, is building […]
Hypercubic, a Fall 2025 Y Combinator-backed startup, is tackling one of the most valuable and least glamorous technology problems in the global economy: the decades-old COBOL codebases running on mainframes that continue to power the core systems of banks, insurers, airlines, telecoms, and retailers. The company is building an AI-native platform to maintain, understand, and […]
Enterprise AI projects tend to fail at a specific, unglamorous step: parsing the documents. Research teams can spend six months building a document pipeline and still watch fewer than ten percent of those projects make it into production, because generic large language model parsers and legacy OCR systems fall apart on the multimodal PDFs, scanned […]
As fraud costs balloon across the internet and KYC-heavy industries juggle an ever-growing stack of identity checks, Didit is pitching a simpler story: one platform, one fast face scan, one predictable per-use price. Founded in 2023 and currently part of Y Combinator’s Winter 2026 cohort, Didit positions itself as “an all-in-one identity platform that lets […]
Sourcebot, an AI code search tool built for massive codebases, is emerging from Y Combinator’s Fall 2025 batch with a message the rest of the AI tooling industry has been slow to embrace. Writing code is no longer the hard part – understanding it is. And for both human engineers and the AI agents increasingly […]
Zalos, a Fall 2025 Y Combinator company, is taking direct aim at the repetitive, time-consuming, and error-prone work that still clogs finance operations at companies of every size. The startup builds AI finance automation software – computer-using agents that log directly into a company’s existing ERP, accounting systems, banking portals, and other CFO tools – […]
Consumer packaged goods brands have long been celebrated for their marketing and product innovation, but their back-office operations remain stuck in the spreadsheet era. Corvera, a Y Combinator–backed startup, is attacking that gap with an AI agent workforce purpose-built for CPG operations – and the early traction suggests the market has been waiting for exactly […]
The customer relationship management category is one of the oldest and most lucrative in enterprise software, but it is also one of the most hated. Sellers complain about pipeline hygiene, support managers complain about data drift, and operations teams complain about the dozens of integrations required to make any of it useful. item, a Y […]
As AI coding agents move from single-user experiments to production workflows, a new kind of bottleneck has emerged on developer laptops: too many agents, all trying to run the same project at once. Ports clash, databases get corrupted, and per-branch setup becomes fragile. Coasts, a Y Combinator–backed startup (Fall 2025), is introducing one of the […]
For two decades, the marketing stack has been organized around a familiar funnel: someone searches Google, lands on a website, and converts through a carefully optimized series of pages. That funnel is starting to break. Increasingly, prospective customers do their research inside ChatGPT, Perplexity, and other AI agents – which then surface a small set […]
