Browse 40 startups in San Francisco working in B2B. Every listing below is matched on location and skill set so you can discover the right company faster. Compare profiles and reach out directly.
Cumulus Labs, a Y Combinator Winter 2026 startup, is betting that the next competitive axis in AI is not model quality but inference economics. The company is building an AI inference optimization platform – what it calls the fastest multimodal inference operating system – aimed squarely at AI teams who want dramatically lower costs and […]
Training data has quietly become one of the most contested assets in artificial intelligence. Frontier labs need staggering volumes of high-quality, diverse, and – increasingly – legally defensible data to push their models forward, yet the supply side of that equation is a mess of scraped corpora, unclear licensing, and reactive lawsuits. Luel, a Y […]
Management consultants have long charged seven-figure fees to do one seemingly simple thing: talk to everyone in a company and figure out what’s broken. Ontora, a San Francisco-based startup in Y Combinator’s Spring 2026 batch, is betting that the whole exercise can be automated. The company has launched an AI operational intelligence platform that interviews […]
Enterprise software has a dirty open secret: the tool is rarely the hard part. Implementation is. Rollouts of ERPs, data platforms, and – increasingly – enterprise AI systems, routinely take months and demand armies of system integrators and forward-deployed engineers to wire up, configure, and tune. Lab0, a San Francisco startup in Y Combinator’s Spring […]
Outbound sales has become an arms race of volume, and small teams are losing. Cold lists, mass sequences, and blanket personalization tools have driven reply rates to historic lows while inboxes become harder to crack. Gojiberry AI, a Y Combinator Spring 2026 company, is pitching a different approach: an AI outbound sales platform with a […]
Developer documentation has always been the quiet infrastructure of software. It determines which APIs get adopted, which SDKs get abandoned, and which products get replaced. Manicule, a Y Combinator Spring 2026 startup, believes that infrastructure is overdue for a rebuild – and that the rebuild looks more like an AI-native studio than a freelance writing […]
Datost, a Y Combinator Spring 2026 company, is out to democratize data work inside the enterprise with a deceptively simple premise: give every team an AI data analyst that has its own computer and lives where the conversation already happens. The startup’s agent, accessible directly in Slack, sees and understands a company’s documents, databases, data […]
The e-commerce playbook of the 2010s – pick a Shopify theme, hire an agency, tweak funnels, and run paid ads – is looking increasingly expensive and slow against a new generation of AI-native competitors. Amboras is positioning itself at the front of that shift. The Y Combinator Spring 2026 startup is building an autonomous AI […]
Kuli, a Y Combinator Spring 2026 company, is rebuilding the AI influencer marketing stack around a single agent that actually watches social video content the way a seasoned marketer would. Where legacy platforms hand marketing teams yet another searchable database and a CRM, Kuli positions itself as the orchestration layer that takes work off their […]
Modern is taking aim at one of the quiet productivity drains of large organizations: the endless stream of low-complexity, high-volume internal requests that clog up IT help desks, HR mailboxes, and finance approval queues. The Y Combinator Spring 2026 company believes AI agents can resolve more than 80 percent of those requests automatically – and […]
