Top SaaS Startups in San Francisco

Browse 10 startups in San Francisco working in SaaS. Every listing below is matched on location and skill set so you can discover the right company faster. Compare profiles and reach out directly.

Signals

San Francisco

Most customer support software is built around a reactive loop: a user runs into a problem, opens a ticket, waits in a queue, and eventually gets an answer. Signals, a Y Combinator Winter 2026 startup, is flipping that model on its head. The company is building an AI customer engagement platform that engages high-value customers […]

Artificial Intelligence B2B SaaS

Frizzle

San Francisco

Frizzle, a Y Combinator Summer 2025 company based in San Francisco, has built an AI product aimed squarely at one of the most stubborn time sinks in American education: grading. Teachers routinely spend more than 10 hours per week – roughly a quarter of all their working time – evaluating student work, especially handwritten math […]

Artificial Intelligence B2B Education

Hypercubic

San Francisco

Hypercubic, a Fall 2025 Y Combinator-backed startup, is tackling one of the most valuable and least glamorous technology problems in the global economy: the decades-old COBOL codebases running on mainframes that continue to power the core systems of banks, insurers, airlines, telecoms, and retailers. The company is building an AI-native platform to maintain, understand, and […]

Artificial Intelligence B2B Developer Tools

Corvera

San Francisco

Consumer packaged goods brands have long been celebrated for their marketing and product innovation, but their back-office operations remain stuck in the spreadsheet era. Corvera, a Y Combinator–backed startup, is attacking that gap with an AI agent workforce purpose-built for CPG operations – and the early traction suggests the market has been waiting for exactly […]

Artificial Intelligence B2B SaaS

Bear

San Francisco

For two decades, the marketing stack has been organized around a familiar funnel: someone searches Google, lands on a website, and converts through a carefully optimized series of pages. That funnel is starting to break. Increasingly, prospective customers do their research inside ChatGPT, Perplexity, and other AI agents – which then surface a small set […]

B2B Generative AI SaaS

Korso

San Francisco

Ask any plant manager where the bottlenecks are and the answer rarely involves the factory floor itself. It is the paperwork around it – the RFQs that need processing, the quotes that need chasing, the suppliers that need reminding, and the production schedules that need rewiring every time reality intrudes. Korso, a Y Combinator Spring […]

AI Manufacturing SaaS

Gojiberry AI

San Francisco

Outbound sales has become an arms race of volume, and small teams are losing. Cold lists, mass sequences, and blanket personalization tools have driven reply rates to historic lows while inboxes become harder to crack. Gojiberry AI, a Y Combinator Spring 2026 company, is pitching a different approach: an AI outbound sales platform with a […]

AI B2B SaaS

Kuli

San Francisco

Kuli, a Y Combinator Spring 2026 company, is rebuilding the AI influencer marketing stack around a single agent that actually watches social video content the way a seasoned marketer would. Where legacy platforms hand marketing teams yet another searchable database and a CRM, Kuli positions itself as the orchestration layer that takes work off their […]

Artificial Intelligence B2B SaaS

Modern

San Francisco

Modern is taking aim at one of the quiet productivity drains of large organizations: the endless stream of low-complexity, high-volume internal requests that clog up IT help desks, HR mailboxes, and finance approval queues. The Y Combinator Spring 2026 company believes AI agents can resolve more than 80 percent of those requests automatically – and […]

AIOps Artificial Intelligence B2B

Gigacatalyst

San Francisco

For years, SaaS vendors have promised configurability – a dropdown here, a custom field there, maybe a Zapier integration if the customer was sophisticated enough to wire one up. Gigacatalyst, a Y Combinator Spring 2026 startup, argues that “configurable” was always a polite word for “not quite customized.” Its answer is to give SaaS companies […]

Artificial Intelligence Enterprise No-code