Top Open Source Startups in San Francisco

Browse 5 startups in San Francisco working in Open Source. Every listing below is matched on location and skill set so you can discover the right company faster. Compare profiles and reach out directly.

superglue

San Francisco

Superglue, a Winter 2025 Y Combinator company, is attacking one of the least glamorous and most fragile layers of the modern enterprise stack: the brittle SQL scripts, cron jobs, and one-off connectors that quietly run most day-to-day operations. Founded in 2024 by Adina Goerres and Stefan Faistenauer, the four-person team is building an open-source platform […]

AI API Enterprise

Onyx

San Francisco

Onyx, a Y Combinator Winter 2024 company, is building the open-source AI chat layer designed to solve one of the most persistent problems in modern work: inside every company is a mountain of knowledge that nobody can find. It is scattered across Google Drive, Slack threads, GitHub repos, Confluence pages, Salesforce notes, Notion wikis, and […]

AI Enterprise NLP

Cactus

San Francisco

Cactus is a Y Combinator Summer 2025 company built on a simple but hard conviction: the next frontier of consumer AI isn’t in the cloud — it’s on the device in your pocket or on your wrist. Founded in 2025 and based in San Francisco, the eight-person team is building a low-latency AI engine optimized […]

AI Artificial Intelligence Developer Tools

Sourcebot

San Francisco

Sourcebot, an AI code search tool built for massive codebases, is emerging from Y Combinator’s Fall 2025 batch with a message the rest of the AI tooling industry has been slow to embrace. Writing code is no longer the hard part – understanding it is. And for both human engineers and the AI agents increasingly […]

Artificial Intelligence B2B Developer Tools

InsForge

San Francisco

InsForge thinks the current generation of backend platforms was built for the wrong user. Databases, authentication systems, and infrastructure APIs have spent the last two decades optimizing for human developers – their cognitive load, their dashboards, their documentation. But with AI coding agents now shouldering more of the actual work of shipping software, InsForge argues […]

Developer Tools Infrastructure Open Source